I've been working on compiling M.A.M.E/M.E.S.S natively on my SL-6000 running pdaXrom RC10 and I'm happy to report some success!
I started with the source for 0.85 (I'm working up to 0.99) and made a few changes to the makefile. So far I've been able to compile full M.E.S.S and the Tiny M.A.M.E. build which only supports Stratofighter and Raiga. The full build of M.A.M.E. segfaults when memory is exausted, but I have a few tricks left to try. With M.E.S.S. I have run Vectrex, Colecovision, and PDP11. I'll be trying Comodore 64 and Timex Sinclair later.
What I need now is some help. Specificaly I need someone that has experience building ipkg files to help me package the M.E.S.S. port, and I need a feed where this can be hosted. For now, I'll start making it available via Shareaza P2P. I'll post here again when I know the file name.
Right now I'm going to concentrate on building a Frontend as well as creating .rc files to organize roms/sounds/artwork/etc...
BTW I'm also working on a port of Daphne for playing Dragon's Lair and Space Ace, but I'm having a hard time with meeting all the dependencies.