Since Gnopernicus is for Gnome it would be a significant effort to port this to the QT based Sharp ROMs. KDE is lacking in the accessibility department, but according to this article:
http://news.zdnet.co.uk/0,39020330,39164598,00.htmThere is an effort under way to make KDE more accessible. I think this is a great idea. The easiest port for Gnopernicus would be to pdaxrom at this time. Looks like a difficult, but rewarding project.