some can, most can't.
Caveats :
- debian arm uses glibc 2.3.x, pdaxrom uses 2.2.5
- softfloat difference
If you search the forums for "debian on pdaxrom", you'll find a way to launch debian apps in pdaX. You'll need some space though. My experience with this is that it works very good! The apps use the optimized X-server and are faster than through X/qt thanks to this. I've been running gnumeric this way as well as the pdaX-version, there's hardly any speed difference.
Chero.