GTD tiddlywiki can be sped up quite a bit, it seems relatively useable in Opera now. In options, turn off animation.
I've also tried deleting lots of wiki entries, so as to reduce the data set, and that seemed to help, albeit now I can get the error that GTDTW wasn't saved properly.
Oh yeah, you have to remember that since you're not using a mouse, you have to tap on the titles of each tiddly in order to make the buttons appear.
I tried it in netfront but it wouldn't finish loading, netfront insisted I connect to the network and when I denied it, it got upset and terminated loading of the page :-/