I have a 12" usb extension that is very flexible.
I have it plugged into the usb host and there is not any strain at all on the usb port.
I would much rather carry a cable than take a chance on damaging the unit.
Also, from what I see, the only thing holding the usb port in place is the fact that it is connected to the pcb.
So how would a full sized port would withstand any more stress than the mini port?
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Yes, the connector is soldered to the PCB by 4 anchors (highlighted in blue) as you can see in the attached jpg from albertr's site.
The full size USB connector is larger then the original so you will only be able to, if you are lucky, use two of the existing anchor holes on one side. That will cause the connector to flex too much and put too much pressure on the the usb leads to the PCB (which shouldn't be used for anchoring in the first place).
The full-size connector will eventually sheer off from the stress. To avoid that you would need to precision drill new anchor holes in the PCB to accomodate the the full-size connector but, since the PCB is quite dense on a Z you risk puncturing a trace and possibly FUBARing you Z. Not worth it in my opinion.